国际麻醉学与复苏杂志   2025, Issue (9): 0-0
    
左室舒张功能障碍患者围术期麻醉管理研究进展
郭楠, 赵平1()
1.中国医科大学附属盛京医院
Perioperative management of left ventricular diastolic dysfunction
 全文:
摘要:

左室舒张功能障碍(left ventricular diastolic dysfunction, LVDD)是指左心室舒张期松弛受损和顺应性下降,导致左心室充盈受损、舒张末期压力增高,甚至引起心肌重塑。随着人口老龄化的进展和床旁超声心动图的普及,越来越多的研究发现LVDD与围手术期不良预后密切相关。本文结合国内外相关文献,就LVDD的定义、病理生理学特点、流行病学、诊断分级、术前评估、术中麻醉管理优化及术后并发症防治等方面进行综述,旨在为LVDD患者非心脏手术的围手术期麻醉管理提供理论依据和实践指导。

关键词: 左室舒张功能障碍;经胸超声心动图;麻醉管理;围手术期
Abstract:

Left ventricular diastolic dysfunction (LVDD) is characterized by impaired diastolic relaxation and reduced compliance, leading to compromised left ventricular filling, elevated end-diastolic pressure, and potential myocardial remodeling. As the population ages and the wide use of point-of-care echocardiography, an increasing number of studies have established a significant correlation between LVDD and adverse perioperative outcomes. This review aims to elucidate the definition, pathophysiological characteristics, epidemiology, and diagnostic grading of LVDD. Additionally, it provides insights and recommendations for preoperative assessment, intraoperative anesthesia management, and prevention of postoperative complications. The goal is to furnish both a theoretical foundation and practical guidance for perioperative anesthesia management in non-cardiac surgical patients with LVDD.

Key words: left ventricular diastolic dysfunction; transthoracic echocardiography; anesthesia management; perioperative