There are many nerve block techniques applied in the operation of breast cancer, compared with the single block technique, the combined application of multiple nerve block techniques can achieve more satisfactory analgesic and anesthetic effects; Combined application of different nerve block can form different block schemes. This article introduces various combined block methods currently used in breast cancer surgery, and summarizes them based on the characteristics of nerve distribution in the surgical area of breast cancer, in order to provide reference for clinical application and research in future.