国际麻醉学与复苏杂志   2024, Issue (12): 0-0
    
术后神经认知功能恢复延迟评估与管理的循证分析
汤灵宇, 陈顺利, 黄厚强, 郑思琳1()
1.西南医科大学附属医院;西南医科大学护理学院
Evidence‑based analysis of evaluation and management of delayed recovery of neurocognitive function after surgery
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摘要:

目的 总结术后神经认知功能恢复延迟(DNCR)管理的最佳证据,为DNCR的防治提供参考。 方法 计算机检索2018年1月至2023年10月BMJ Best Practice、Up To Date、JBI循证卫生保健中心(JBI)、OVID、国家指南协作网(GIN)、英国国家卫生与临床优化研究所(NICE)、苏格兰院际指南网(SIGN)、美国麻醉医师协会(ASA)、欧洲麻醉医师协会(ESAIC)、全球脑健康学会(GCBH)、PubMed、Web of Science核心合集数据库、中国知网(CNKI)、维普资讯(VIP)、中国生物医学文献数据库、万方数据、医脉通指南网、中华医学会麻醉学分会官网内关于DNCR评估与管理的证据,包括指南、专家共识、临床决策、系统评价。由2名研究者进行文献质量评价和资料提取。 结果 共纳入13篇文献,包括1篇指南、9篇专家共识、1篇临床决策、2篇系统评价。最终在风险因素筛查、认知评估、麻醉优化及药物审查、疼痛管理、器官供给与需求反馈监测管理、抗应激管理、认知支持治疗、多学科团队合作、教育培训9个方面形成了29条最佳证据。 结论 为DNCR的管理提供了循证依据,临床人员在使用时应结合临床实际,遵循个体化原则,联合多学科团队实施多模式多维度围手术期管理。

关键词: 术后神经认知功能恢复延迟; 术后神经认知障碍; 循证医学
Abstract:

Objective To summarize the best evidence for managing delayed neurocognitive recovery (DNCR) after surgery and provide reference for the prevention and treatment of DNCR. Methods Retrieved BMJ Best Practice, Up To Date, Joanna Briggs Institute (JBI), OVID, Guidelines International Network (GIN), the National Institute for Health and Care Excellence (NICE), the Scottish Intercollegiate Guidelines Network (SIGN), the American Society of Anesthesiologists (ASA), the European Society of Anesthesiology and Intensive Care (ESAIC), the Global Council on Brain Health (GCBH), PubMed, the Database of Web of Science Core Collection, China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), Chinese Biomedical Literature Database, Wanfang Database, Yimai Tong Guideline Network, and the Chinese Society of Anesthesiology website from January 2018 to October 2023 for evidence on DNCR assessment and management, including guidelines, expert consensus, clinical decisions, and systematic reviews. Two researchers evaluated the quality of the literature and extracted relevant data. Results A total of 13 documents were included, comprising 1 guideline, 9 expert consensus statements, 1 clinical decision, and 2 systematic reviews. There were 29 optimal evidence recommendations across nine areas: risk factor screening, cognitive assessment, anesthesia optimization and medication review, pain management, monitoring of organ supply and demand feedback, stress management, cognitive support therapy, multidisciplinary team collaboration, and education and training. Conclusions This study provides evidence‑based guidance for managing DNCR. Clinical personnel should tailor these recommendations to clinical realities, adhere to individualized principles, and implement multimodal and multidimensional perioperative management with multidisciplinary team collaboration.

Key words: Postoperative delayed neurocognitive recovery; Postoperative cognitive dysfunction; Evidence‑based medicine