国际麻醉学与复苏杂志   2024, Issue (8): 0-0
    
入院即刻行髂筋膜间隙阻滞对老年THA患者围手术期焦虑及睡眠质量的影响
袁从虎, 王孝庆, 陆容祥, 李向南, 葛亚丽, 高巨1()
1.盐城市第三人民医院
Effect of fascia iliaca compartment block immediately upon admission on perioperative anxiety and sleep quality in elderly patients undergoing total hip arthroplasty
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摘要:

目的 探讨入院即刻行连续髂筋膜间隙阻滞(FICB)超前镇痛对老年股骨颈骨折(FNF)患者全髋关节置换术(THA)围手术期焦虑及睡眠质量的影响。 方法 选择全麻下行THA的老年FNF患者74例,按随机数字表法分为两组:FICB(F组,36例)和常规组(C组,38例)。F组入院后行连续FICB,手术当日麻醉诱导插管成功后撤除FICB;C组入院后常规给予静脉滴注酮咯酸氨丁三醇15 mg,每日1次,持续至手术当日。记录两组患者入院即刻(T0)、行FICB后30 min(C组为相同时点)(T1)、手术当日早晨(T2)、术后6 h(T3)、术后24 h(T4)、术后48 h(T5)时的焦虑视觉模拟量表(VAS‑a)评分及静息、运动视觉模拟评分法(VAS)疼痛评分,记录两组患者入院当日、术前1 d、术后1~7 d的睡眠评价量表(LSEQ)评分,记录两组患者术中丙泊酚及瑞芬太尼用量、术后镇痛泵首次按压时间、术后48 h内镇痛泵有效按压次数、补救镇痛例数、术后不良反应[术后恶心呕吐(PONV)、尿潴留、呼吸抑制]发生率、首次下床活动时间。 结果 与T0时比较,F组T1~T5时及C组T3~T5时VAS‑a评分、静息及运动VAS疼痛评分降低(均P<0.05)。与C组比较:F组T1~T3时VAS‑a评分、静息及运动VAS评分较低(均P<0.05);入院当天、术前1 d及术后1~3 d LSEQ评分较高(均P<0.05);术中丙泊酚、瑞芬太尼用量,术后48 h内镇痛泵有效按压次数及补救镇痛例数较少(均P<0.05);术后镇痛泵首次按压时间较长(P<0.05);PONV、尿潴留发生率较低(均P<0.05);首次下床活动时间较短(P<0.05)。两组患者其余指标差异无统计学意义(均P>0.05)。 结论 入院即刻行连续FICB超前镇痛可以有效缓解老年FNF患者THA围手术期焦虑,改善围手术期睡眠质量,减少阿片类及非甾体抗炎药使用,降低术后不良反应发生率,促进术后早期下床活动。

关键词: 围手术期; 焦虑; 睡眠质量; 髂筋膜间隙阻滞; 老年人; 股骨颈骨折
Abstract:

Objective To evaluate the effect of continuous fascia iliaca compartment block (FICB) immediately upon admission as preemptive analgesia on perioperative anxiety and sleep quality in elderly patients with femoral neck fracture (FNF) undergoing total hip arthroplasty (THA). Methods A total of 74 elderly patients with FNF, who underwent elective THA under general anesthesia, were selected. According to the random number table method, they were divided into two groups: a FICB group (group F, n=36) and a routine group (group C, n=38). Patients in group F received continuous FICB after admission, which was withdrawn after successful anesthesia induction and intubation on the day of surgery. Those in group C were routinely administered after admission with 15 mg ketorolac tromethamine through drip infusion once a day until the day of surgery. Then, the Visual Analog Scales for Anxiety (VAS‑a) scores, and the Visual Analog Scale (VAS) scores at resting and during movement were recorded at immediate admission (T0), at post‑FICB 30 min (group C at the same time point) (T1), on the morning of surgery (T2), at post‑operation 6 h (T3), at post‑operation 24 h (T4), and at post‑operation 48 h (T5). The Leeds Sleep Evaluation Questionnaire (LSEQ) scores on the day of admission, 1 d before operation, and at post‑operation days 1‒7 were recorded. The intraoperative dosages of propofol and remifentanil, the time to first pressing of analgesic pump after surgery, the number of effective pressing within 48 h after surgery, the number of rescue analgesia cases, the incidence of postoperative adverse events [postoperative nausea and vomiting (PONV), urinary retention, and respiratory depression], and the time to first off‑bed activities were recorded. Results Compared with T0, the VAS‑a scores, as well as both resting and exercise VAS scores, were significantly lower at T1-T5 in group F and at T3-T5 in group C (all P<0.05). Compared with group C, group F had significantly lower VAS‑a scores, resting and exercise VAS scores at T1-T3 (all P<0.05); significantly higher LSEQ scores on the day of admission, 1 d before operation, and 1‒3 d after operation (all P<0.05); significantly lower intraoperative dosage of propofol and remifentanil, fewer effective presses of the analgesic pump within 48 h after surgery, and fewer patients requiring ketorolac tromethamine for rescue analgesia (all P<0.05); a significantly later time to first press of the analgesic pump after surgery (P<0.05); significantly lower incidence of PONV and urinary retention (all P<0.05); and a significantly earlier time to first ambulation (P<0.05). There was no statistical difference in other indicators between the two groups (all P>0.05). Conclusions Continuous FICB as preemptive analgesia immediately upon admission can effectively alleviate perioperative anxiety and improves perioperative sleep quality in elderly patients with FNF undergoing THA. It also reduces the use of opioids and non steroidal antiinflammatory drug, decreases the incidence of postoperative adverse events, and promotes early postoperative off‑bed activities.

Key words: Perioperative; Anxiety; Sleep quality; Fascia iliaca compartment block; Aged; Femoral neck fracture; Total hip arthroplasty