Abstract: An appropriate blood volume has a great influence on the prognosis of patients with traumatic brain injury (TBI). Stud⁃
ies have shown that fluid overload leads to complications such as tissue edema, lung injury and poor wound healing. Insufficient fluid in⁃
creases the risk of hypotension, reduces perfusion of vital organs such as the heart, brain, and kidney, even leads to organ failure. How to op⁃
timize the intraoperative fluid management strategy is one of the most common problems for anesthesiologists. This article will discuss the
three aspects: Liquid properties (crystalloid, colloid, hypertonic saline, and mannitol), liquid dosage[open fluid therapy, restricted fluid
therapy, goal directed fluid therapy (GDFT)], Intravascular volume monitoring. Addressing the advantages and disadvantages of different
fluid management strategies aims to guide intraoperative fluid management in TBI patients and provide references for new studies.
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