Background　Wnt signaling is a highly conserved pathway and plays a critical role in neurogenesis.　Objective　To explain the role of canonical Wnt signaling on neurogenesis.　Content　This review summarized the latest general studies of canonical Wnt/β-catenin signaling on neurogenesis including proliferation, differentiation, asymmetric cell division of neural stem cells and adult neurogenesis.　Trend　Understanding how Wnt signaling effects neurogenesis will be helpful for new strategies of clinical usage.