Ｏｂｊｅｃｔｉｖｅ　To assess the efficacy of laryngeal mask airway I-gel(LMA I-gel) in patients undergoing microvascular decompression of facial nerve.　Methods　Ninety ASA patients withⅠ or Ⅱ of both sexes, aged 20-55 y, body mass index of 18-25 kg/m2, of Mallampati Ⅰ-Ⅲ, undergoing microvascular decompression of facial nerve, were completely randomly divided into 3 groups(n=30): I-gel group (group I), Supreme group (group S), endotracheal intubation group(group Q). The time spent for intubation and success rate of intubation for the first time were recorded in the three groups, Oropharyngeal leak pressure and fiberoptic laryngoscopy scores were observed in lateral position in group I and group S. Vital signs were monitered after entering the operating room(T0), before intubation (T1), intubation(T2), before extubation(T3) extubation immediately(T4). The extubation time of laryngeal mask and tracheal catheter and consciousness recovery time were observed. The postoperative cough, sore throat, nausea, vomiting and other adverse reactions were recorded too.　Results　Regarding the time spent for intubation, group I and group S was shorter than group Q[(12±3), (16±4) s vs (30±6) s](P<0.05), group I was the shorter than group S(P<0.05). There was no significant difference in the success rate of intubation for the first time in the 3 groups(P>0.05). Oropharyngeal leak pressure in lateral position was more higher in group I than in group S[(28±3) cmH2O(1 cmH2O=0.098 kPa) vs (24±4) cmH2O](P<0.05). Compared MAP[(86±10), (85±9) mmHg(1 mmHg=0.133 kPa) vs (105±11) mmHg, (91±11), (92±12) mmHg vs (106±14) mmHg] and HR [(75±9), (76±11) bpm vs (89±12) bpm, (83±9), (82±11) bpm vs (93±12) bpm] at T2 and T4, group I and group S were significantly less than group Q(P<0.05). The recovery time and extubation time were longest in group Q[(2.5±1.4), (2.8±1.2) min vs (5.1±1.8) min, (3.8±1.1), (3.7±1.0) min vs (6.2±1.5) min](P<0.05). Cough case numbers were significantly highest in group Q(33.3%)(P<0.05), sore throat case numbers were significantly lower in group I and group S than in group Q(6.7%, 16.7% vs 30%)(P<0.05). There was no significant difference in the incidence of other adverse reactions(P>0.05).　Conclusions　Laryngeal mask I-gel, laryngeal mask supreme and tracheal can be used effectively for microvascular decompression of facial nerve, but laryngeal mask I-gel can provide adequate ventilation during operation with less complications, more easy insertion and more stable hemodynamics.