国际麻醉学与复苏杂志   2013, Issue (8): 12-12
    
微小RNA与心肌缺血/再灌注损伤研究进展
曹嵩, 刘云, 喻田1()
1.遵义医学院
Advance of relations between microRNAs and myocardial ischemia-reperfusion injury
 全文:
摘要:

【摘要】背景 近年研究表明MicroRNA(miRNA, miR)参与了心肌缺血-再灌注损伤(Ischemia-reperfusion injury,IRI)的进程。目的 综述miRNA参与心肌IRI的研究进展。 内容 概述miRNA及与心肌IRI有关的miRNA的作用,并作展望。趋势 miRNA与心肌IRI密切相关。以miRNA为靶点的治疗将可能被用于心肌保护。

关键词: 【关键词】MicroRNA;缺血-再灌注损伤;心肌保护
Abstract:

【Abstract】Background MicroRNA(miRNA, miR) plays a role in myocardial ischemia-reperfusion injury(IRI) process. Objective Reviewing research progresses on correlations between miRNA and myocardial IRI. Content Making an overview of miRNA and IRI-related miRNAs and giving a prospect of them. Trend MiRNAs are closely correlated with myocardial IRI. MiRNA targeted treatments probably will be used to achieve myocardial protection.

Key words: 【Key words】 MicroRNA; Ischemia-reperfusion injury (IRI); Myocardial protection